Automated and fast building of three-dimensional RNA structures

Building tertiary structures of non-coding RNA is required to understand their functions and design new molecules. Current algorithms of RNA tertiary structure prediction give satisfactory accuracy only for small size and simple topology and many of them need manual manipulation. Here, we present an...

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Detalles Bibliográficos
Autores principales: Zhao, Yunjie, Huang, Yangyu, Gong, Zhou, Wang, Yanjie, Man, Jianfen, Xiao, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471093/
https://www.ncbi.nlm.nih.gov/pubmed/23071898
http://dx.doi.org/10.1038/srep00734
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author Zhao, Yunjie
Huang, Yangyu
Gong, Zhou
Wang, Yanjie
Man, Jianfen
Xiao, Yi
author_facet Zhao, Yunjie
Huang, Yangyu
Gong, Zhou
Wang, Yanjie
Man, Jianfen
Xiao, Yi
author_sort Zhao, Yunjie
collection PubMed
description Building tertiary structures of non-coding RNA is required to understand their functions and design new molecules. Current algorithms of RNA tertiary structure prediction give satisfactory accuracy only for small size and simple topology and many of them need manual manipulation. Here, we present an automated and fast program,3dRNA, for RNA tertiary structure prediction with reasonable accuracy for RNAs of larger size and complex topology.
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spelling pubmed-34710932012-10-15 Automated and fast building of three-dimensional RNA structures Zhao, Yunjie Huang, Yangyu Gong, Zhou Wang, Yanjie Man, Jianfen Xiao, Yi Sci Rep Article Building tertiary structures of non-coding RNA is required to understand their functions and design new molecules. Current algorithms of RNA tertiary structure prediction give satisfactory accuracy only for small size and simple topology and many of them need manual manipulation. Here, we present an automated and fast program,3dRNA, for RNA tertiary structure prediction with reasonable accuracy for RNAs of larger size and complex topology. Nature Publishing Group 2012-10-15 /pmc/articles/PMC3471093/ /pubmed/23071898 http://dx.doi.org/10.1038/srep00734 Text en Copyright © 2012, Macmillan Publishers Limited. All rights reserved http://creativecommons.org/licenses/by-nc-sa/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial-ShareALike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/
spellingShingle Article
Zhao, Yunjie
Huang, Yangyu
Gong, Zhou
Wang, Yanjie
Man, Jianfen
Xiao, Yi
Automated and fast building of three-dimensional RNA structures
title Automated and fast building of three-dimensional RNA structures
title_full Automated and fast building of three-dimensional RNA structures
title_fullStr Automated and fast building of three-dimensional RNA structures
title_full_unstemmed Automated and fast building of three-dimensional RNA structures
title_short Automated and fast building of three-dimensional RNA structures
title_sort automated and fast building of three-dimensional rna structures
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471093/
https://www.ncbi.nlm.nih.gov/pubmed/23071898
http://dx.doi.org/10.1038/srep00734
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