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Detection of Rare Genomic Variants from Pooled Sequencing Using SPLINTER

As DNA sequencing technology has markedly advanced in recent years(2), it has become increasingly evident that the amount of genetic variation between any two individuals is greater than previously thought(3). In contrast, array-based genotyping has failed to identify a significant contribution of c...

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Detalles Bibliográficos
Autores principales: Vallania, Francesco, Ramos, Enrique, Cresci, Sharon, Mitra, Robi D., Druley, Todd E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471313/
https://www.ncbi.nlm.nih.gov/pubmed/22760212
http://dx.doi.org/10.3791/3943