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Centrosome Aberrations Associated with Cellular Senescence and p53 Localization at Supernumerary Centrosomes

Centrosome overduplication or amplification has been observed in many human cancers and in premalignant tissue, but the mechanisms leading to such centrosome aberrations are not fully understood. We previously showed that abnormal mitotic cells with supernumerary centrosomes increase with replicativ...

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Detalles Bibliográficos
Autor principal: Ohshima, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471474/
https://www.ncbi.nlm.nih.gov/pubmed/23091651
http://dx.doi.org/10.1155/2012/217594

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