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Substance P (SP) induces expression of functional corticotropin-releasing hormone receptor-1 (CRHR-1) in human mast cells

Corticotropin-releasing hormone (CRH) is secreted under stress and regulates the hypothalamic-pituitary-adrenal (HPA) axis. However, CRH is also secreted outside the brain where it exerts pro-inflammatory effects through activation of mast cells, which are increasingly implicated in immunity and inf...

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Detalles Bibliográficos
Autores principales: Asadi, Shahrzad, Alysandratos, Konstantinos-Dionysios, Angelidou, Asimenia, Miniati, Alexandra, Sismanopoulos, Nikolaos, Vasiadi, Magdalini, Zhang, Bodi, Kalogeromitros, Dimitrios, Theoharides, Theoharis C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471564/
https://www.ncbi.nlm.nih.gov/pubmed/22089831
http://dx.doi.org/10.1038/jid.2011.334