The potential benefit of stem cell therapy after stroke: an update

Stroke is a leading cause of death and disability worldwide. Stem cell therapy is an emerging therapeutic modality with evidence of significant benefits in preclinical stroke models. A number of phase I and II clinical trials have now been completed, with several more currently under way. Translatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Banerjee, Soma, Williamson, Deborah A, Habib, Nagy, Chataway, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471602/
https://www.ncbi.nlm.nih.gov/pubmed/23091389
http://dx.doi.org/10.2147/VHRM.S25745
_version_ 1782246449039278080
author Banerjee, Soma
Williamson, Deborah A
Habib, Nagy
Chataway, Jeremy
author_facet Banerjee, Soma
Williamson, Deborah A
Habib, Nagy
Chataway, Jeremy
author_sort Banerjee, Soma
collection PubMed
description Stroke is a leading cause of death and disability worldwide. Stem cell therapy is an emerging therapeutic modality with evidence of significant benefits in preclinical stroke models. A number of phase I and II clinical trials have now been completed, with several more currently under way. Translation to the bedside, however, remains a long way off, and there are many questions that remain unanswered. This review will summarize the current evidence and ongoing clinical trials worldwide, and explore the challenges to making this a realistic treatment option for the future.
format Online
Article
Text
id pubmed-3471602
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher Dove Medical Press
record_format MEDLINE/PubMed
spelling pubmed-34716022012-10-22 The potential benefit of stem cell therapy after stroke: an update Banerjee, Soma Williamson, Deborah A Habib, Nagy Chataway, Jeremy Vasc Health Risk Manag Review Stroke is a leading cause of death and disability worldwide. Stem cell therapy is an emerging therapeutic modality with evidence of significant benefits in preclinical stroke models. A number of phase I and II clinical trials have now been completed, with several more currently under way. Translation to the bedside, however, remains a long way off, and there are many questions that remain unanswered. This review will summarize the current evidence and ongoing clinical trials worldwide, and explore the challenges to making this a realistic treatment option for the future. Dove Medical Press 2012 2012-10-10 /pmc/articles/PMC3471602/ /pubmed/23091389 http://dx.doi.org/10.2147/VHRM.S25745 Text en © 2012 Banerjee et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Review
Banerjee, Soma
Williamson, Deborah A
Habib, Nagy
Chataway, Jeremy
The potential benefit of stem cell therapy after stroke: an update
title The potential benefit of stem cell therapy after stroke: an update
title_full The potential benefit of stem cell therapy after stroke: an update
title_fullStr The potential benefit of stem cell therapy after stroke: an update
title_full_unstemmed The potential benefit of stem cell therapy after stroke: an update
title_short The potential benefit of stem cell therapy after stroke: an update
title_sort potential benefit of stem cell therapy after stroke: an update
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471602/
https://www.ncbi.nlm.nih.gov/pubmed/23091389
http://dx.doi.org/10.2147/VHRM.S25745
work_keys_str_mv AT banerjeesoma thepotentialbenefitofstemcelltherapyafterstrokeanupdate
AT williamsondeboraha thepotentialbenefitofstemcelltherapyafterstrokeanupdate
AT habibnagy thepotentialbenefitofstemcelltherapyafterstrokeanupdate
AT chatawayjeremy thepotentialbenefitofstemcelltherapyafterstrokeanupdate
AT banerjeesoma potentialbenefitofstemcelltherapyafterstrokeanupdate
AT williamsondeboraha potentialbenefitofstemcelltherapyafterstrokeanupdate
AT habibnagy potentialbenefitofstemcelltherapyafterstrokeanupdate
AT chatawayjeremy potentialbenefitofstemcelltherapyafterstrokeanupdate

Ejemplares similares