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Chemical Communication between the Endophytic Fungus Paraconiothyrium Variabile and the Phytopathogen Fusarium oxysporum

Paraconiothyrium variabile, one of the specific endophytic fungi isolated from the host plant Cephalotaxus harringtonia, possesses the faculty to inhibit the growth of common phytopathogens, thus suggesting a role in its host protection. A strong antagonism between the endophyte P. variabile and Fus...

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Autores principales: Combès, Audrey, Ndoye, Idrissa, Bance, Caroline, Bruzaud, Jérôme, Djediat, Chakib, Dupont, Joëlle, Nay, Bastien, Prado, Soizic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471838/
https://www.ncbi.nlm.nih.gov/pubmed/23077591
http://dx.doi.org/10.1371/journal.pone.0047313
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author Combès, Audrey
Ndoye, Idrissa
Bance, Caroline
Bruzaud, Jérôme
Djediat, Chakib
Dupont, Joëlle
Nay, Bastien
Prado, Soizic
author_facet Combès, Audrey
Ndoye, Idrissa
Bance, Caroline
Bruzaud, Jérôme
Djediat, Chakib
Dupont, Joëlle
Nay, Bastien
Prado, Soizic
author_sort Combès, Audrey
collection PubMed
description Paraconiothyrium variabile, one of the specific endophytic fungi isolated from the host plant Cephalotaxus harringtonia, possesses the faculty to inhibit the growth of common phytopathogens, thus suggesting a role in its host protection. A strong antagonism between the endophyte P. variabile and Fusarium oxysporum was observed and studied using optic and electronic microscopies. A disorganization of the mycelium of F. oxysporum was thus noticed. Interestingly, the biological effect of the main secondary metabolites isolated from P. variabile against F. oxysporum did not account for this strong antagonism. However, a metabolomic approach of pure fungal strains and confrontation zones using the data analysis tool XCMS were analyzed and pointed out a competition-induced metabolite production by the endophyte in the presence of the phytopathogen. Subsequent MS/MS fragmentations permitted to identify one of the induced metabolites as 13-oxo-9,11-octadecadienoic acid and highlighted a negative modulation of the biosynthesis of beauvericin, one of the most potent mycotoxin of F. oxysporum, during the competition with the endophyte.
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spelling pubmed-34718382012-10-17 Chemical Communication between the Endophytic Fungus Paraconiothyrium Variabile and the Phytopathogen Fusarium oxysporum Combès, Audrey Ndoye, Idrissa Bance, Caroline Bruzaud, Jérôme Djediat, Chakib Dupont, Joëlle Nay, Bastien Prado, Soizic PLoS One Research Article Paraconiothyrium variabile, one of the specific endophytic fungi isolated from the host plant Cephalotaxus harringtonia, possesses the faculty to inhibit the growth of common phytopathogens, thus suggesting a role in its host protection. A strong antagonism between the endophyte P. variabile and Fusarium oxysporum was observed and studied using optic and electronic microscopies. A disorganization of the mycelium of F. oxysporum was thus noticed. Interestingly, the biological effect of the main secondary metabolites isolated from P. variabile against F. oxysporum did not account for this strong antagonism. However, a metabolomic approach of pure fungal strains and confrontation zones using the data analysis tool XCMS were analyzed and pointed out a competition-induced metabolite production by the endophyte in the presence of the phytopathogen. Subsequent MS/MS fragmentations permitted to identify one of the induced metabolites as 13-oxo-9,11-octadecadienoic acid and highlighted a negative modulation of the biosynthesis of beauvericin, one of the most potent mycotoxin of F. oxysporum, during the competition with the endophyte. Public Library of Science 2012-10-15 /pmc/articles/PMC3471838/ /pubmed/23077591 http://dx.doi.org/10.1371/journal.pone.0047313 Text en © 2012 Combès et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Combès, Audrey
Ndoye, Idrissa
Bance, Caroline
Bruzaud, Jérôme
Djediat, Chakib
Dupont, Joëlle
Nay, Bastien
Prado, Soizic
Chemical Communication between the Endophytic Fungus Paraconiothyrium Variabile and the Phytopathogen Fusarium oxysporum
title Chemical Communication between the Endophytic Fungus Paraconiothyrium Variabile and the Phytopathogen Fusarium oxysporum
title_full Chemical Communication between the Endophytic Fungus Paraconiothyrium Variabile and the Phytopathogen Fusarium oxysporum
title_fullStr Chemical Communication between the Endophytic Fungus Paraconiothyrium Variabile and the Phytopathogen Fusarium oxysporum
title_full_unstemmed Chemical Communication between the Endophytic Fungus Paraconiothyrium Variabile and the Phytopathogen Fusarium oxysporum
title_short Chemical Communication between the Endophytic Fungus Paraconiothyrium Variabile and the Phytopathogen Fusarium oxysporum
title_sort chemical communication between the endophytic fungus paraconiothyrium variabile and the phytopathogen fusarium oxysporum
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471838/
https://www.ncbi.nlm.nih.gov/pubmed/23077591
http://dx.doi.org/10.1371/journal.pone.0047313
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