Spironolactone Rescues Dot1a-Af9-Mediated Repression of Endothelin-1 and Improves Kidney Injury in Streptozotocin-Induced Diabetic Rats

The molecular mechanism linking aldosterone and endothelin-1 in the development of diabetic nephropathy has not been completely elucidated. Here, we provide evidence showing that streptozotocin-induced diabetic rats have significantly increased aldosterone and endothelin-1 in the kidney tissue and m...

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Detalles Bibliográficos
Autores principales: Zhou, Qiaoling, Liu, Kanghan, Wu, Hongyu, Chen, Lihe, Pouranan, Veeraragoo, Yuan, Mingxia, Xiao, Zhou, Peng, Weisheng, Xiang, Ao, Tang, Rong, Zhang, Wenzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471839/
https://www.ncbi.nlm.nih.gov/pubmed/23077601
http://dx.doi.org/10.1371/journal.pone.0047360

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