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Leukemia Inhibitory Factor Protects Axons in Experimental Autoimmune Encephalomyelitis via an Oligodendrocyte-Independent Mechanism
Leukemia inhibitory factor (LIF) and Ciliary Neurotrophic factor (CNTF) are members of the interleukin-6 family of cytokines, defined by use of the gp130 molecule as an obligate receptor. In the murine experimental autoimmune encephalomyelitis (EAE) model, antagonism of LIF and genetic deletion of C...
Autores principales: | Gresle, Melissa M., Alexandrou, Estella, Wu, Qizhu, Egan, Gary, Jokubaitis, Vilija, Ayers, Margaret, Jonas, Anna, Doherty, William, Friedhuber, Anna, Shaw, Gerry, Sendtner, Michael, Emery, Ben, Kilpatrick, Trevor, Butzkueven, Helmut |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471848/ https://www.ncbi.nlm.nih.gov/pubmed/23077604 http://dx.doi.org/10.1371/journal.pone.0047379 |
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