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Promotion of Glioblastoma Cell Motility by Enhancer of Zeste Homolog 2 (EZH2) Is Mediated by AXL Receptor Kinase

Enhancer of zeste homolog 2 (EZH2) is the catalytic subunit of the Polycomb-repressive complex 2 (PRC2) that epigenetically silences gene transcription through histone H3 lysine trimethylation (H3K27me3). EZH2 has been implicated in stem cell maintenance and is overexpressed in hematological and sol...

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Detalles Bibliográficos
Autores principales: Ott, Martina, Litzenburger, Ulrike M., Sahm, Felix, Rauschenbach, Katharina J., Tudoran, Ruxandra, Hartmann, Christian, Marquez, Victor E., von Deimling, Andreas, Wick, Wolfgang, Platten, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471855/
https://www.ncbi.nlm.nih.gov/pubmed/23077658
http://dx.doi.org/10.1371/journal.pone.0047663