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Autocrine IFNγ Controls the Regulatory Function of Lymphoproliferative Double Negative T Cells
TCRαβ(+) CD4(−)CD8(−)NK(−) double negative T cells (DN T cells) can act as regulatory T cells to inhibit allograft rejection and autoimmunity. Their role in graft-versus-host disease and mechanisms of suppression remain elusive. In this study, we demonstrate that DN T cells can inhibit CD4(+) T cell...
Autores principales: | Juvet, Stephen C., Han, Mei, Vanama, Ramesh, Joe, Betty, Kim, Edward Y., Zhao, Fei Linda, Jeon, Caroline, Adeyi, Oyedele, Zhang, Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471870/ https://www.ncbi.nlm.nih.gov/pubmed/23077665 http://dx.doi.org/10.1371/journal.pone.0047732 |
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