Differential Mitochondrial Toxicity Screening and Multi-Parametric Data Analysis

Early evaluation of new drug entities for their potential to cause mitochondrial dysfunction is becoming an important task for drug development. Multi-parametric high-content screening (mp-HCS) of mitochondrial toxicity holds promise as a lead in-vitro strategy for drug testing and safety evaluation...

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Detalles Bibliográficos
Autores principales: Tsiper, Maria V., Sturgis, Jennifer, Avramova, Larisa V., Parakh, Shilpa, Fatig, Raymond, Juan-García, Ana, Li, Nianyu, Rajwa, Bartek, Narayanan, Padma, Qualls, C. W., Robinson, J. Paul, Davisson, V. Jo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471932/
https://www.ncbi.nlm.nih.gov/pubmed/23077490
http://dx.doi.org/10.1371/journal.pone.0045226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471932/
https://www.ncbi.nlm.nih.gov/pubmed/23077490
http://dx.doi.org/10.1371/journal.pone.0045226

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