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5-Fluorouracil Nanoparticles Inhibit Hepatocellular Carcinoma via Activation of the p53 Pathway in the Orthotopic Transplant Mouse Model
Biodegradable polymer nanoparticle drug delivery systems provide targeted drug delivery, improved pharmacokinetic and biodistribution, enhanced drug stability and fewer side effects. These drug delivery systems are widely used for delivering cytotoxic agents. In the present study, we synthesized GC/...
Autores principales: | Cheng, Mingrong, He, Bing, Wan, Tao, Zhu, Weiping, Han, Jiang, Zha, Bingbing, Chen, Houxiang, Yang, Fengxiao, Li, Qing, Wang, Wei, Xu, Hongzhi, Ye, Tao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471936/ https://www.ncbi.nlm.nih.gov/pubmed/23077553 http://dx.doi.org/10.1371/journal.pone.0047115 |
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