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Enterohaemorrhagic Escherichia coli haemolysin is cleaved and inactivated by serine protease EspPα

The haemolysin from enterohaemorrhagic Escherichia coli (EHEC-Hly) and the serine protease EspPα are putative virulence factors of EHEC. We investigated the interplay between these secreted factors and demonstrate that EspPα cleaves the 107 kDa large EHEC-Hly. Degradation was observed when purified...

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Detalles Bibliográficos
Autores principales:	Brockmeyer, Jens, Aldick, Thomas, Soltwisch, Jens, Zhang, Wenlan, Tarr, Philip I, Weiss, André, Dreisewerd, Klaus, Müthing, Johannes, Bielaszewska, Martina, Karch, Helge
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2011
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472028/ https://www.ncbi.nlm.nih.gov/pubmed/21352460 http://dx.doi.org/10.1111/j.1462-2920.2011.02431.x

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