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Environmental tobacco smoke and stress as risk factors for miscarriage and preterm births

BACK GROUND: Exposure of pregnant women to environmental tobacco smoke has been shown to be associated with low birth weight. Many studies have suggested that stress have a role in the etiology of preterm birth. AIMS: This study carried out from June 2008 to March 2009 to find the relation between e...

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Autores principales: Arffin, Farha, AL-Bayaty, Fouad H., Hassan, Jamiyah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472053/
https://www.ncbi.nlm.nih.gov/pubmed/22718098
http://dx.doi.org/10.1007/s00404-012-2417-0
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author Arffin, Farha
AL-Bayaty, Fouad H.
Hassan, Jamiyah
author_facet Arffin, Farha
AL-Bayaty, Fouad H.
Hassan, Jamiyah
author_sort Arffin, Farha
collection PubMed
description BACK GROUND: Exposure of pregnant women to environmental tobacco smoke has been shown to be associated with low birth weight. Many studies have suggested that stress have a role in the etiology of preterm birth. AIMS: This study carried out from June 2008 to March 2009 to find the relation between environmental tobacco smoke, stress and miscarriage and preterm births. METHODS: A total of 33 subjects consisted of multiparous pregnant women that were in their early third trimester were chosen for this investigation. Subjects were divided into test group women with adverse pregnancy outcome, control group women with successful pregnancy. Four ml of unstimulated whole saliva were collected. The concentrations of cotinine and cortisol were evaluated using commercially available ELISA kit. RESULTS: Pregnancies in which the average standardized cortisol during history of previous miscarriage(s) which occurred within 6th–27th week or/and history of preterm labor which occurred within 28th–36th weeks of gestation, demonstrated higher cortisol level (1.0201 ± 0.1855 ng/ml) compared to control group 0.9757 ± 0.2860 ng/ml (P = 0.323); statistical analysis showed no significant differences. Women of control group were more likely to be environmental tobacco smoke exposed (1.2714 ± 1.7639 ng/ml) than women with miscarriage and preterm births (0.9889 ± 0.5498 ng/ml). CONCLUSION: The results from this primarily study demonstrated no association between cotinine, cortisol, miscarriage and preterm births.
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spelling pubmed-34720532012-10-18 Environmental tobacco smoke and stress as risk factors for miscarriage and preterm births Arffin, Farha AL-Bayaty, Fouad H. Hassan, Jamiyah Arch Gynecol Obstet General Gynecology BACK GROUND: Exposure of pregnant women to environmental tobacco smoke has been shown to be associated with low birth weight. Many studies have suggested that stress have a role in the etiology of preterm birth. AIMS: This study carried out from June 2008 to March 2009 to find the relation between environmental tobacco smoke, stress and miscarriage and preterm births. METHODS: A total of 33 subjects consisted of multiparous pregnant women that were in their early third trimester were chosen for this investigation. Subjects were divided into test group women with adverse pregnancy outcome, control group women with successful pregnancy. Four ml of unstimulated whole saliva were collected. The concentrations of cotinine and cortisol were evaluated using commercially available ELISA kit. RESULTS: Pregnancies in which the average standardized cortisol during history of previous miscarriage(s) which occurred within 6th–27th week or/and history of preterm labor which occurred within 28th–36th weeks of gestation, demonstrated higher cortisol level (1.0201 ± 0.1855 ng/ml) compared to control group 0.9757 ± 0.2860 ng/ml (P = 0.323); statistical analysis showed no significant differences. Women of control group were more likely to be environmental tobacco smoke exposed (1.2714 ± 1.7639 ng/ml) than women with miscarriage and preterm births (0.9889 ± 0.5498 ng/ml). CONCLUSION: The results from this primarily study demonstrated no association between cotinine, cortisol, miscarriage and preterm births. Springer-Verlag 2012-06-21 2012 /pmc/articles/PMC3472053/ /pubmed/22718098 http://dx.doi.org/10.1007/s00404-012-2417-0 Text en © The Author(s) 2012 https://creativecommons.org/licenses/by/4.0/ This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
spellingShingle General Gynecology
Arffin, Farha
AL-Bayaty, Fouad H.
Hassan, Jamiyah
Environmental tobacco smoke and stress as risk factors for miscarriage and preterm births
title Environmental tobacco smoke and stress as risk factors for miscarriage and preterm births
title_full Environmental tobacco smoke and stress as risk factors for miscarriage and preterm births
title_fullStr Environmental tobacco smoke and stress as risk factors for miscarriage and preterm births
title_full_unstemmed Environmental tobacco smoke and stress as risk factors for miscarriage and preterm births
title_short Environmental tobacco smoke and stress as risk factors for miscarriage and preterm births
title_sort environmental tobacco smoke and stress as risk factors for miscarriage and preterm births
topic General Gynecology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472053/
https://www.ncbi.nlm.nih.gov/pubmed/22718098
http://dx.doi.org/10.1007/s00404-012-2417-0
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