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The RNA-binding motif 45 (RBM45) protein accumulates in inclusion bodies in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP) patients
RNA-binding protein pathology now represents one of the best characterized pathologic features of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration patients with TDP-43 or FUS pathology (FTLD-TDP and FTLD-FUS). Using liquid chromatography tandem mass spectrometry, we identifi...
Autores principales: | Collins, Mahlon, Riascos, David, Kovalik, Tina, An, Jiyan, Krupa, Kelly, Krupa, Kristin, Hood, Brian L., Conrads, Thomas P., Renton, Alan E., Traynor, Bryan J., Bowser, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472056/ https://www.ncbi.nlm.nih.gov/pubmed/22993125 http://dx.doi.org/10.1007/s00401-012-1045-x |
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