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Promoter hypermethylation-induced transcriptional down-regulation of the gene MYCT1 in laryngeal squamous cell carcinoma

BACKGROUND: MYCT1, previously named MTLC, is a novel candidate tumor suppressor gene. MYCT1 was cloned from laryngeal squamous cell cancer (LSCC) and has been found to be down-regulated in LSCC; however, the regulatory details have not been fully elucidated. METHODS: Here, we sought to investigate t...

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Detalles Bibliográficos
Autores principales:	Yang, Min, Li, Wei, Liu, Yi-Ying, Fu, Shuang, Qiu, Guang-Bin, Sun, Kai-Lai, Fu, Wei-Neng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472177/ https://www.ncbi.nlm.nih.gov/pubmed/22672838 http://dx.doi.org/10.1186/1471-2407-12-219

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