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Iteration method for predicting essential proteins based on orthology and protein-protein interaction networks

BACKGROUND: Identification of essential proteins plays a significant role in understanding minimal requirements for the cellular survival and development. Many computational methods have been proposed for predicting essential proteins by using the topological features of protein-protein interaction...

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Detalles Bibliográficos
Autores principales: Peng, Wei, Wang, Jianxin, Wang, Weiping, Liu, Qing, Wu, Fang-Xiang, Pan, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472210/
https://www.ncbi.nlm.nih.gov/pubmed/22808943
http://dx.doi.org/10.1186/1752-0509-6-87