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Immunogenicity when utilizing adenovirus serotype 4 and 5 vaccines expressing circumsporozoite protein in naïve and Adenovirus (Ad5) immune mice
BACKGROUND: Induction of potent long lasting effector T cell responses against liver stage malaria antigens strongly correlates with protection from malaria. While Adenovirus serotype 5 (Ad5) based malaria vaccine platforms have the ability to induce potent effector T cell responses against transgen...
Autores principales: | Schuldt, Nathaniel J, Aldhamen, Yasser A, Godbehere-Roosa, Sarah, Seregin, Sergey S, Kousa, Youssef A, Amalfitano, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472263/ https://www.ncbi.nlm.nih.gov/pubmed/22720732 http://dx.doi.org/10.1186/1475-2875-11-209 |
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