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Genome-wide expression analysis upon constitutive activation of the HacA bZIP transcription factor in Aspergillus niger reveals a coordinated cellular response to counteract ER stress
BACKGROUND: HacA/Xbp1 is a conserved bZIP transcription factor in eukaryotic cells which regulates gene expression in response to various forms of secretion stress and as part of secretory cell differentiation. In the present study, we replaced the endogenous hacA gene of an Aspergillus niger strain...
Autores principales: | Carvalho, Neuza DSP, Jørgensen, Thomas R, Arentshorst, Mark, Nitsche, Benjamin M, van den Hondel, Cees AMJJ, Archer, David B, Ram, Arthur FJ |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472299/ https://www.ncbi.nlm.nih.gov/pubmed/22846479 http://dx.doi.org/10.1186/1471-2164-13-350 |
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