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Mechanisms of Dendritic Cell Lysosomal Killing of Cryptococcus

Cryptococcus neoformans is an opportunistic pulmonary fungal pathogen that disseminates to the CNS causing fatal meningitis in immunocompromised patients. Dendritic cells (DCs) phagocytose C. neoformans following inhalation. Following uptake, cryptococci translocate to the DC lysosomal compartment a...

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Detalles Bibliográficos
Autores principales:	Hole, Camaron R., Bui, Hoang, Wormley, Floyd L., Wozniak, Karen L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472389/ https://www.ncbi.nlm.nih.gov/pubmed/23074646 http://dx.doi.org/10.1038/srep00739

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