Cargando…

SNP Genotyping Identifies New Signatures of Selection in a Deep Sample of West African Plasmodium falciparum Malaria Parasites

We used a high-density single-nucleotide polymorphism array to genotype 75 Plasmodium falciparum isolates recently collected from Senegal and The Gambia to search for signals of selection in this malaria endemic region. We found little geographic or temporal stratification of the genetic diversity a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Amambua-Ngwa, Alfred, Park, Daniel J., Volkman, Sarah K., Barnes, Kayla G., Bei, Amy K., Lukens, Amanda K., Sene, Papa, Van Tyne, Daria, Ndiaye, Daouda, Wirth, Dyann F., Conway, David J., Neafsey, Daniel E., Schaffner, Stephen F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Letters
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472499/ https://www.ncbi.nlm.nih.gov/pubmed/22688945 http://dx.doi.org/10.1093/molbev/mss151

Ejemplares similares

Changes in drug sensitivity and anti-malarial drug resistance mutations over time among Plasmodium falciparum parasites in Senegal
por: Van Tyne, Daria, et al.
Publicado: (2013)

Genetic Surveillance Detects Both Clonal and Epidemic Transmission of Malaria following Enhanced Intervention in Senegal
por: Daniels, Rachel, et al.
Publicado: (2013)

Polymorphism in dhfr/dhps genes, parasite density and ex vivo response to pyrimethamine in Plasmodium falciparum malaria parasites in Thies, Senegal()
por: Ndiaye, Daouda, et al.
Publicado: (2013)

Genetic relatedness analysis reveals the cotransmission of genetically related Plasmodium falciparum parasites in Thiès, Senegal
por: Wong, Wesley, et al.
Publicado: (2017)

Hybrid selection for sequencing pathogen genomes from clinical samples
por: Melnikov, Alexandre, et al.
Publicado: (2011)

Temporal changes in Plasmodium falciparum reticulocyte binding protein homolog 2b (PfRh2b) in Senegal and The Gambia
por: Diédhiou, Cyrille K., et al.
Publicado: (2019)

A general SNP-based molecular barcode for Plasmodium falciparum identification and tracking
por: Daniels, Rachel, et al.
Publicado: (2008)

An Adjustable Gas-Mixing Device to Increase Feasibility of In Vitro Culture of Plasmodium falciparum Parasites in the Field
por: Bei, Amy K., et al.
Publicado: (2014)

Human cerebral malaria and Plasmodium falciparum genotypes in Malawi
por: Milner, Danny A, et al.
Publicado: (2012)

Genome-wide SNP genotyping highlights the role of natural selection in Plasmodium falciparum population divergence
por: Neafsey, Daniel E, et al.
Publicado: (2008)

Genetic surveillance for monitoring the impact of drug use on Plasmodium falciparum populations
por: Ndiaye, Yaye Die, et al.
Publicado: (2021)

Identification and Functional Validation of the Novel Antimalarial Resistance Locus PF10_0355 in Plasmodium falciparum
por: Van Tyne, Daria, et al.
Publicado: (2011)

De Novo Mutations Resolve Disease Transmission Pathways in Clonal Malaria
por: Redmond, Seth N, et al.
Publicado: (2018)

Plasmodium falciparum genomic surveillance reveals spatial and temporal trends, association of genetic and physical distance, and household clustering
por: Sy, Mouhamad, et al.
Publicado: (2022)

RDTs as a source of DNA to study Plasmodium falciparum drug resistance in isolates from Senegal and the Comoros Islands
por: Papa Mze, Nasserdine, et al.
Publicado: (2015)

R (H): a genetic metric for measuring intrahost Plasmodium falciparum relatedness and distinguishing cotransmission from superinfection
por: Wong, Wesley, et al.
Publicado: (2022)

Detection of low-density Plasmodium falciparum infections using amplicon deep sequencing
por: Early, Angela M., et al.
Publicado: (2019)

Long-distance transmission patterns modelled from SNP barcodes of Plasmodium falciparum infections in The Gambia
por: Amambua-Ngwa, Alfred, et al.
Publicado: (2019)

Mutations in Plasmodium falciparum actin-binding protein coronin confer reduced artemisinin susceptibility
por: Demas, Allison R., et al.
Publicado: (2018)

Methods to Increase the Sensitivity of High Resolution Melting Single Nucleotide Polymorphism Genotyping in Malaria
por: Daniels, Rachel, et al.
Publicado: (2015)

Evidence of non-Plasmodium falciparum malaria infection in Kédougou, Sénégal
por: Daniels, Rachel F., et al.
Publicado: (2017)

A global transcriptional analysis of Plasmodium falciparum malaria reveals a novel family of telomere-associated lncRNAs
por: Broadbent, Kate M, et al.
Publicado: (2011)

hmmIBD: software to infer pairwise identity by descent between haploid genotypes
por: Schaffner, Stephen F., et al.
Publicado: (2018)

Evaluating the performance of Plasmodium falciparum genetics for inferring National Malaria Control Program reported incidence in Senegal
por: Wong, Wesley, et al.
Publicado: (2023)

Analysis of pfhrp2 genetic diversity in Senegal and implications for use of rapid diagnostic tests
por: Deme, Awa B, et al.
Publicado: (2014)

Genetic background and PfKelch13 affect artemisinin susceptibility of PfCoronin mutants in Plasmodium falciparum
por: Sharma, Aabha I., et al.
Publicado: (2020)

Amplicon deep sequencing of kelch13 in Plasmodium falciparum isolates from Senegal
por: Gaye, Amy, et al.
Publicado: (2020)

Pre-amplification methods for tracking low-grade Plasmodium falciparum populations during scaled-up interventions in Southern Zambia
por: Mharakurwa, Sungano, et al.
Publicado: (2014)

COIL: a methodology for evaluating malarial complexity of infection using likelihood from single nucleotide polymorphism data
por: Galinsky, Kevin, et al.
Publicado: (2015)

Identification of Collateral Sensitivity to Dihydroorotate Dehydrogenase Inhibitors in Plasmodium falciparum
por: Ross, Leila Saxby, et al.
Publicado: (2018)

Plasmodium falciparum gene expression measured directly from tissue during human infection
por: Van Tyne, Daria, et al.
Publicado: (2014)

Molecular epidemiology of Plasmodium falciparum by multiplexed amplicon deep sequencing in Senegal
por: Ndiaye, Tolla, et al.
Publicado: (2020)

Allelic diversity of MSP1 and MSP2 repeat loci correlate with levels of malaria endemicity in Senegal and Nigerian populations
por: Oboh, Mary A., et al.
Publicado: (2021)

High resolution melting: a useful field-deployable method to measure dhfr and dhps drug resistance in both highly and lowly endemic Plasmodium populations
por: Ndiaye, Yaye Dié, et al.
Publicado: (2017)

Use of a Plasmodium vivax genetic barcode for genomic surveillance and parasite tracking in Sri Lanka
por: Dewasurendra, Rajika L., et al.
Publicado: (2020)

Host-mediated selection impacts the diversity of Plasmodium falciparum antigens within infections
por: Early, Angela M., et al.
Publicado: (2018)

Ex vivo susceptibility and genotyping of Plasmodium falciparum isolates from Pikine, Senegal
por: Mbaye, Aminata, et al.
Publicado: (2017)

Plasmodium falciparum Cyclic Amine Resistance Locus (PfCARL), a Resistance Mechanism for Two Distinct Compound Classes
por: Magistrado, Pamela A., et al.
Publicado: (2016)

Genetic evidence for imported malaria and local transmission in Richard Toll, Senegal
por: Daniels, Rachel F., et al.
Publicado: (2020)

Modeling the genetic relatedness of Plasmodium falciparum parasites following meiotic recombination and cotransmission
por: Wong, Wesley, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_e6q8g1p7hm6k28kc91gaoj7krq