The confluence of radiotherapy and immunotherapy

Radiotherapy (RT) has been considered a local modality and outcomes have emphasized local and regional control of tumors. Recent data suggests that RT may activate the immune system and the combination of radiation therapy and immune therapies may have the potential to improve both local and distant...

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Detalles Bibliográficos
Autores principales: Burnette, Byron, Fu, Yang-Xin, Weichselbaum, Ralph R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472545/
https://www.ncbi.nlm.nih.gov/pubmed/23087904
http://dx.doi.org/10.3389/fonc.2012.00143
Descripción
Sumario:Radiotherapy (RT) has been considered a local modality and outcomes have emphasized local and regional control of tumors. Recent data suggests that RT may activate the immune system and the combination of radiation therapy and immune therapies may have the potential to improve both local and distant control of tumor deposits. Below we review principals underlying the concepts of combining both modalities.

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