The confluence of radiotherapy and immunotherapy

Radiotherapy (RT) has been considered a local modality and outcomes have emphasized local and regional control of tumors. Recent data suggests that RT may activate the immune system and the combination of radiation therapy and immune therapies may have the potential to improve both local and distant...

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Detalles Bibliográficos
Autores principales: Burnette, Byron, Fu, Yang-Xin, Weichselbaum, Ralph R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472545/
https://www.ncbi.nlm.nih.gov/pubmed/23087904
http://dx.doi.org/10.3389/fonc.2012.00143
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author Burnette, Byron
Fu, Yang-Xin
Weichselbaum, Ralph R.
author_facet Burnette, Byron
Fu, Yang-Xin
Weichselbaum, Ralph R.
author_sort Burnette, Byron
collection PubMed
description Radiotherapy (RT) has been considered a local modality and outcomes have emphasized local and regional control of tumors. Recent data suggests that RT may activate the immune system and the combination of radiation therapy and immune therapies may have the potential to improve both local and distant control of tumor deposits. Below we review principals underlying the concepts of combining both modalities.
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spelling pubmed-34725452012-10-19 The confluence of radiotherapy and immunotherapy Burnette, Byron Fu, Yang-Xin Weichselbaum, Ralph R. Front Oncol Oncology Radiotherapy (RT) has been considered a local modality and outcomes have emphasized local and regional control of tumors. Recent data suggests that RT may activate the immune system and the combination of radiation therapy and immune therapies may have the potential to improve both local and distant control of tumor deposits. Below we review principals underlying the concepts of combining both modalities. Frontiers Media S.A. 2012-10-16 /pmc/articles/PMC3472545/ /pubmed/23087904 http://dx.doi.org/10.3389/fonc.2012.00143 Text en Copyright © Burnette, Fu and Weichselbaum. http://www.frontiersin.org/licenseagreement This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/) , which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc.
spellingShingle Oncology
Burnette, Byron
Fu, Yang-Xin
Weichselbaum, Ralph R.
The confluence of radiotherapy and immunotherapy
title The confluence of radiotherapy and immunotherapy
title_full The confluence of radiotherapy and immunotherapy
title_fullStr The confluence of radiotherapy and immunotherapy
title_full_unstemmed The confluence of radiotherapy and immunotherapy
title_short The confluence of radiotherapy and immunotherapy
title_sort confluence of radiotherapy and immunotherapy
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472545/
https://www.ncbi.nlm.nih.gov/pubmed/23087904
http://dx.doi.org/10.3389/fonc.2012.00143
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