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Structural Basis for ASPP2 Recognition by the Tumor Suppressor p73
Tumor suppressors p53, p63 and p73 comprise a family of stress-responsive transcription factors with distinct functions in development and tumor suppression. Most human cancers lose p53 function, yet all three proteins are capable of inducing apoptosis or cellular senescence. Mechanisms are therefor...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472557/ https://www.ncbi.nlm.nih.gov/pubmed/22917970 http://dx.doi.org/10.1016/j.jmb.2012.08.005 |