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The inoculum effect and band-pass bacterial response to periodic antibiotic treatment
The inoculum effect (IE) refers to the decreasing efficacy of an antibiotic with increasing bacterial density. It represents a unique strategy of antibiotic tolerance and it can complicate design of effective antibiotic treatment of bacterial infections. To gain insight into this phenomenon, we have...
Autores principales: | Tan, Cheemeng, Phillip Smith, Robert, Srimani, Jaydeep K, Riccione, Katherine A, Prasada, Sameer, Kuehn, Meta, You, Lingchong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Molecular Biology Organization
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472685/ https://www.ncbi.nlm.nih.gov/pubmed/23047527 http://dx.doi.org/10.1038/msb.2012.49 |
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