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Ultrasound-Assisted Extraction of Carnosic Acid and Rosmarinic Acid Using Ionic Liquid Solution from Rosmarinus officinalis

Ionic liquid based, ultrasound-assisted extraction was successfully applied to the extraction of phenolcarboxylic acids, carnosic acid and rosmarinic acid, from Rosmarinus officinalis. Eight ionic liquids, with different cations and anions, were investigated in this work and [C(8)mim]Br was selected...

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Detalles Bibliográficos
Autores principales: Zu, Ge, Zhang, Rongrui, Yang, Lei, Ma, Chunhui, Zu, Yuangang, Wang, Wenjie, Zhao, Chunjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472728/
https://www.ncbi.nlm.nih.gov/pubmed/23109836
http://dx.doi.org/10.3390/ijms130911027
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author Zu, Ge
Zhang, Rongrui
Yang, Lei
Ma, Chunhui
Zu, Yuangang
Wang, Wenjie
Zhao, Chunjian
author_facet Zu, Ge
Zhang, Rongrui
Yang, Lei
Ma, Chunhui
Zu, Yuangang
Wang, Wenjie
Zhao, Chunjian
author_sort Zu, Ge
collection PubMed
description Ionic liquid based, ultrasound-assisted extraction was successfully applied to the extraction of phenolcarboxylic acids, carnosic acid and rosmarinic acid, from Rosmarinus officinalis. Eight ionic liquids, with different cations and anions, were investigated in this work and [C(8)mim]Br was selected as the optimal solvent. Ultrasound extraction parameters, including soaking time, solid–liquid ratio, ultrasound power and time, and the number of extraction cycles, were discussed by single factor experiments and the main influence factors were optimized by response surface methodology. The proposed approach was demonstrated as having higher efficiency, shorter extraction time and as a new alternative for the extraction of carnosic acid and rosmarinic acid from R. officinalis compared with traditional reference extraction methods. Ionic liquids are considered to be green solvents, in the ultrasound-assisted extraction of key chemicals from medicinal plants, and show great potential.
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spelling pubmed-34727282012-10-29 Ultrasound-Assisted Extraction of Carnosic Acid and Rosmarinic Acid Using Ionic Liquid Solution from Rosmarinus officinalis Zu, Ge Zhang, Rongrui Yang, Lei Ma, Chunhui Zu, Yuangang Wang, Wenjie Zhao, Chunjian Int J Mol Sci Article Ionic liquid based, ultrasound-assisted extraction was successfully applied to the extraction of phenolcarboxylic acids, carnosic acid and rosmarinic acid, from Rosmarinus officinalis. Eight ionic liquids, with different cations and anions, were investigated in this work and [C(8)mim]Br was selected as the optimal solvent. Ultrasound extraction parameters, including soaking time, solid–liquid ratio, ultrasound power and time, and the number of extraction cycles, were discussed by single factor experiments and the main influence factors were optimized by response surface methodology. The proposed approach was demonstrated as having higher efficiency, shorter extraction time and as a new alternative for the extraction of carnosic acid and rosmarinic acid from R. officinalis compared with traditional reference extraction methods. Ionic liquids are considered to be green solvents, in the ultrasound-assisted extraction of key chemicals from medicinal plants, and show great potential. Molecular Diversity Preservation International (MDPI) 2012-09-05 /pmc/articles/PMC3472728/ /pubmed/23109836 http://dx.doi.org/10.3390/ijms130911027 Text en © 2012 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0 This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Zu, Ge
Zhang, Rongrui
Yang, Lei
Ma, Chunhui
Zu, Yuangang
Wang, Wenjie
Zhao, Chunjian
Ultrasound-Assisted Extraction of Carnosic Acid and Rosmarinic Acid Using Ionic Liquid Solution from Rosmarinus officinalis
title Ultrasound-Assisted Extraction of Carnosic Acid and Rosmarinic Acid Using Ionic Liquid Solution from Rosmarinus officinalis
title_full Ultrasound-Assisted Extraction of Carnosic Acid and Rosmarinic Acid Using Ionic Liquid Solution from Rosmarinus officinalis
title_fullStr Ultrasound-Assisted Extraction of Carnosic Acid and Rosmarinic Acid Using Ionic Liquid Solution from Rosmarinus officinalis
title_full_unstemmed Ultrasound-Assisted Extraction of Carnosic Acid and Rosmarinic Acid Using Ionic Liquid Solution from Rosmarinus officinalis
title_short Ultrasound-Assisted Extraction of Carnosic Acid and Rosmarinic Acid Using Ionic Liquid Solution from Rosmarinus officinalis
title_sort ultrasound-assisted extraction of carnosic acid and rosmarinic acid using ionic liquid solution from rosmarinus officinalis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472728/
https://www.ncbi.nlm.nih.gov/pubmed/23109836
http://dx.doi.org/10.3390/ijms130911027
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