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Methylation of p15(INK4b) and Expression of ANRIL on Chromosome 9p21 Are Associated with Coronary Artery Disease

BACKGROUND: Genome-wide association studies have identified that multiple single nucleiotide polymorphisms on chromosome 9p21 are tightly associated with coronary artery disease (CAD). However, the mechanism linking this risk locus to CAD remains unclear. METHODOLOGY/PRINCIPAL FINDINGS: The methylat...

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Detalles Bibliográficos
Autores principales:	Zhuang, Jianhui, Peng, Wenhui, Li, Hailing, Wang, Wei, Wei, Yidong, Li, Weiming, Xu, Yawei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3473029/ https://www.ncbi.nlm.nih.gov/pubmed/23091611 http://dx.doi.org/10.1371/journal.pone.0047193

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