Single Liver Lobe Repopulation with Wildtype Hepatocytes Using Regional Hepatic Irradiation Cures Jaundice in Gunn Rats

BACKGROUND AND AIMS: Preparative hepatic irradiation (HIR), together with mitotic stimulation of hepatocytes, permits extensive hepatic repopulation by transplanted hepatocytes in rats and mice. However, whole liver HIR is associated with radiation-induced liver disease (RILD), which limits its pote...

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Detalles Bibliográficos
Autores principales: Zhou, Hongchao, Dong, Xinyuan, Kabarriti, Rafi, Chen, Yong, Avsar, Yesim, Wang, Xia, Ding, Jianqiang, Liu, Laibin, Fox, Ira J., Roy-Chowdhury, Jayanta, Roy-Chowdhury, Namita, Guha, Chandan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3473037/
https://www.ncbi.nlm.nih.gov/pubmed/23091601
http://dx.doi.org/10.1371/journal.pone.0046775

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