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Expression of the native cholera toxin B subunit gene and assembly as functional oligomers in transgenic tobacco chloroplasts

The B subunits of enterotoxigenic Escherichia coli (LTB) and cholera toxin of Vibrio cholerae (CTB) are candidate vaccine antigens. Integration of an unmodified CTB-coding sequence into chloroplast genomes (up to 10,000 copies per cell), resulted in the accumulation of up to 4.1% of total soluble to...

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Detalles Bibliográficos
Autores principales:	Daniell, Henry, Lee, Seung-Bum, Panchal, Tanvi, Wiebe, Peter O
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Academic Press. 2001
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3473180/ https://www.ncbi.nlm.nih.gov/pubmed/11531335 http://dx.doi.org/10.1006/jmbi.2001.4921

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