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Overwhelming response to Dabrafenib in a patient with double BRAF mutation (V600E; V600M) metastatic malignant melanoma

The recent findings brought the necessity of testing the mutational status of a series of genes which had been already identified as responsible for melanomas development and progression, such as BRAF, CKIT and PTEN: the consequent results are, in fact, essential to guide the assessment of the novel...

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Detalles Bibliográficos
Autores principales: Ponti, Giovanni, Tomasi, Aldo, Pellacani, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3473234/
https://www.ncbi.nlm.nih.gov/pubmed/23031422
http://dx.doi.org/10.1186/1756-8722-5-60