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In depth comparison of an individual’s DNA and its lymphoblastoid cell line using whole genome sequencing

BACKGROUND: A detailed analysis of whole genomes can be now achieved with next generation sequencing. Epstein Barr Virus (EBV) transformation is a widely used strategy in clinical research to obtain an unlimited source of a subject’s DNA. Although the mechanism of transformation and immortalization...

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Detalles Bibliográficos
Autores principales:	Nickles, Dorothee, Madireddy, Lohith, Yang, Shan, Khankhanian, Pouya, Lincoln, Steve, Hauser, Stephen L, Oksenberg, Jorge R, Baranzini, Sergio E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3473256/ https://www.ncbi.nlm.nih.gov/pubmed/22974163 http://dx.doi.org/10.1186/1471-2164-13-477

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