IκBα deficiency in brain leads to elevated basal neuroinflammation and attenuated response following traumatic brain injury: implications for functional recovery

BACKGROUND: The transcription factor NFκB is an important mediator of cell survival and inflammation in the immune system. In the central nervous system (CNS), NFκB signaling has been implicated in regulating neuronal survival following acute pathologic damage such as traumatic brain injury (TBI) an...

Descripción completa

Detalles Bibliográficos
Autores principales: Lian, Hong, Shim, David J, Gaddam, Samson SK, Rodriguez-Rivera, Jennifer, Bitner, Brittany R, Pautler, Robia G, Robertson, Claudia S, Zheng, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3473257/
https://www.ncbi.nlm.nih.gov/pubmed/22992283
http://dx.doi.org/10.1186/1750-1326-7-47

Ejemplares similares

Ejemplares similares