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Inhibition of Opioid Transmission at the μ-Opioid Receptor Prevents Both Food Seeking and Binge-Like Eating
Endogenous opioids, and in particular μ-opioid receptors, have been linked to hedonic and rewarding mechanisms engaged during palatable food intake. The aim of this study was to investigate the effects of GSK1521498, a novel μ-opioid receptor antagonist, on food-seeking behavior and on binge-like ea...
Autores principales: | Giuliano, Chiara, Robbins, Trevor W, Nathan, Pradeep J, Bullmore, Edward T, Everitt, Barry J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3473330/ https://www.ncbi.nlm.nih.gov/pubmed/22805601 http://dx.doi.org/10.1038/npp.2012.128 |
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