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Antihyperalgesic activity of nucleoside transport inhibitors in models of inflammatory pain in guinea pigs

BACKGROUND AND METHODS: The role of the endogenous purine nucleoside, adenosine, in nociception is well established. Inhibition of the equilibrative nucleoside transporter (ENT1) prevents adenosine uptake into cells, and could therefore enhance the antinociceptive properties of adenosine. The effect...

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Detalles Bibliográficos
Autores principales: Maes, Sabine S, Pype, Stefan, Hoffmann, Vincent LH, Biermans, Maria, Meert, Theo F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474157/
https://www.ncbi.nlm.nih.gov/pubmed/23091396
http://dx.doi.org/10.2147/JPR.S35108

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