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MGAT2 deficiency ameliorates high-fat diet-induced obesity and insulin resistance by inhibiting intestinal fat absorption in mice

BACKGROUND: Resynthesis of triglycerides in enterocytes of the small intestine plays a critical role in the absorption of dietary fat. Acyl-CoA:monoacylglycerol acyltransferase-2 (MGAT2) is highly expressed in the small intestine and catalyzes the synthesis of diacylglycerol from monoacylglycerol an...

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Detalles Bibliográficos
Autores principales: Tsuchida, Takuma, Fukuda, Sayaka, Aoyama, Hisanori, Taniuchi, Nobuhiko, Ishihara, Tomomi, Ohashi, Noriko, Sato, Hiroko, Wakimoto, Koji, Shiotani, Masaharu, Oku, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474177/
https://www.ncbi.nlm.nih.gov/pubmed/22698140
http://dx.doi.org/10.1186/1476-511X-11-75