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Proinflammatory and prothrombotic effects on human vascular endothelial cells of Immune-cell-derived LIGHT

OBJECTIVE: LIGHT (TNFSF 14) belongs to the tumor necrosis factor superfamily and is expressed by activated T cells as well as various types of antigen presenting cells. LIGHT binds to its cellular receptors TR2 and LTßR and has a co-stimulatory role in T cell activation. Here, we compared the relati...

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Detalles Bibliográficos
Autores principales: Celik, S, Shankar, V, Richter, A, Hippe, H-J, Akhavanpoor, M, Bea, F, Erbel, C, Urban, S, Blank, N, Wambsganss, N, Katus, HA, Dengler, TJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474183/
https://www.ncbi.nlm.nih.gov/pubmed/19380287
http://dx.doi.org/10.1186/2047-783X-14-4-147