Cargando…

Estrogen Regulates MAPK-Related Genes through Genomic and Nongenomic Interactions between IGF-I Receptor Tyrosine Kinase and Estrogen Receptor-Alpha Signaling Pathways in Human Uterine Leiomyoma Cells

Estrogen and growth factors play a major role in uterine leiomyoma (UtLM) growth possibly through interactions of receptor tyrosine kinases (RTKs) and estrogen receptor-alpha (ERα) signaling. We determined the genomic and nongenomic effects of 17β-estradiol (E(2)) on IGF-IR/MAPKp44/42 signaling and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Linda, Moore, Alicia B., Castro, Lysandra, Gao, Xiaohua, Huynh, Hoang-Long C., Klippel, Michelle, Flagler, Norris D., Lu, Yi, Kissling, Grace E., Dixon, Darlene
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474284/ https://www.ncbi.nlm.nih.gov/pubmed/23094148 http://dx.doi.org/10.1155/2012/204236

Ejemplares similares

Cadmium and Proliferation in Human Uterine Leiomyoma Cells: Evidence of a Role for EGFR/MAPK Pathways but Not Classical Estrogen Receptor Pathways
por: Gao, Xiaohua, et al.
Publicado: (2014)

ERα36, a variant of estrogen receptor α, is predominantly localized in mitochondria of human uterine smooth muscle and leiomyoma cells
por: Yan, Yitang, et al.
Publicado: (2017)

Epigenetic regulation of transcription factor promoter regions by low-dose genistein through mitogen-activated protein kinase and mitogen-and-stress activated kinase 1 nongenomic signaling
por: Yu, Linda, et al.
Publicado: (2016)

The Natural History of Uterine Leiomyomas: Morphometric Concordance with Concepts of Interstitial Ischemia and Inanosis
por: Flake, Gordon P., et al.
Publicado: (2013)

Human uterine leiomyoma-derived fibroblasts stimulate uterine leiomyoma cell proliferation and collagen type I production, and activate RTKs and TGF beta receptor signaling in coculture
por: Moore, Alicia B, et al.
Publicado: (2010)

Nongenomic mechanisms of physiological estrogen-mediated dopamine efflux
por: Alyea, Rebecca A, et al.
Publicado: (2009)

Nongenomic effects of estrogens on signal transduction pathways in estrogen-sensitive carcinoma cell lines
por: Djahansouzi, S, et al.
Publicado: (2001)

Selective estrogen receptor modulator with estrogen does not affect the proliferation and apoptosis of uterine leiomyoma cells
por: Lv, Shu-Lan, et al.
Publicado: (2020)

Erratum: “Hydroxylated Polybrominated Biphenyl Ethers Exert Estrogenic Effects via Nongenomic G Protein–Coupled Estrogen Receptor Mediated Pathways”
por: Cao, Lin-Ying, et al.
Publicado: (2018)

Cooperation of Genomic and Rapid Nongenomic Actions of Estrogens in Synaptic Plasticity
por: Lai, Yu-Jie, et al.
Publicado: (2016)

Rapid nongenomic estrogen signaling controls alcohol drinking behavior
por: Zallar, L.J., et al.
Publicado: (2023)

“Metalloestrogenic” effects of cadmium downstream of G protein-coupled estrogen receptor and mitogen-activated protein kinase pathways in human uterine fibroid cells
por: Yu, Linda, et al.
Publicado: (2021)

Obesity enhances nongenomic estrogen receptor crosstalk with the PI3K/Akt and MAPK pathways to promote in vitro measures of breast cancer progression
por: Bowers, Laura W, et al.
Publicado: (2013)

Estrogen receptor subtype mediated anti-inflammation and vasorelaxation via genomic and nongenomic actions in septic mice
por: Zhang, Luyun, et al.
Publicado: (2023)

Anthocyanins Activate Membrane Estrogen Receptors With Nanomolar Potencies to Elicit a Nongenomic Vascular Response Via NO Production
por: Calfío, Camila, et al.
Publicado: (2021)

Impact of Genetic Variants in Estrogen Receptor-β Gene in the Etiology of Uterine Leiomyomas
por: Bharathi, Chitroju, et al.
Publicado: (2019)

Controllable drug uptake and nongenomic response through estrogen-anchored cyclodextrin drug complex
por: Yin, Juan-Juan, et al.
Publicado: (2015)

Measurement of Phenolic Environmental Estrogens in Women with Uterine Leiomyoma
por: Shen, Yang, et al.
Publicado: (2013)

Membrane estrogen receptor-α-mediated nongenomic actions of phytoestrogens in GH(3)/B(6)/F(10 )pituitary tumor cells
por: Jeng, Yow-Jiun, et al.
Publicado: (2009)

Estrogen Receptors and Estrogen-Induced Uterine Vasodilation in Pregnancy
por: Bai, Jin, et al.
Publicado: (2020)

Targeting mutant estrogen receptors
por: Wardell, Suzanne E, et al.
Publicado: (2019)

Short‐term tetrabromobisphenol A exposure promotes fibrosis of human uterine fibroid cells in a 3D culture system through TGF‐beta signaling
por: Liu, Jingli, et al.
Publicado: (2022)

Rat Uterine Oxytocin Receptor and Estrogen Receptor α and β mRNA Levels are Regulated by Estrogen Through Multiple Estrogen Receptors
por: MURATA, Takuya, et al.
Publicado: (2013)

Estrogen receptor transcription and transactivation: Estrogen receptor alpha and estrogen receptor beta - regulation by selective estrogen receptor modulators and importance in breast cancer
por: S Katzenellenbogen, Benita, et al.
Publicado: (2000)

Estrogen, Estrogen Receptor and Lung Cancer
por: Hsu, Li-Han, et al.
Publicado: (2017)

Estrogen and estrogen receptors in kidney diseases
por: Ma, Hao-Yang, et al.
Publicado: (2021)

Interactions of dietary estrogens with human estrogen receptors and the effect on estrogen receptor-estrogen response element complex formation.
por: Nikov, G N, et al.
Publicado: (2000)

Estrogen weakens muscle endurance via estrogen receptor-p38 MAPK-mediated orosomucoid (ORM) suppression
por: Sun, Yang, et al.
Publicado: (2018)

Roles of Estrogen, Estrogen Receptors, and Estrogen-Related Receptors in Skeletal Muscle: Regulation of Mitochondrial Function
por: Yoh, Kenta, et al.
Publicado: (2023)

Estrogen-Induced Nongenomic Calcium Signaling Inhibits Lipopolysaccharide-Stimulated Tumor Necrosis Factor α Production in Macrophages
por: Liu, Limin, et al.
Publicado: (2013)

Molecular mechanism of estrogen–estrogen receptor signaling
por: Yaşar, Pelin, et al.
Publicado: (2016)

Role of Estrogen Receptor β, G-Protein Coupled Estrogen Receptor and Estrogen-Related Receptors in Endometrial and Ovarian Cancer
por: Schüler-Toprak, Susanne, et al.
Publicado: (2023)

Tyrosine Phosphatase Shp2 Mediates the Estrogen Biological Action in Breast Cancer via Interaction with the Estrogen Extranuclear Receptor
por: Li, Jun, et al.
Publicado: (2014)

Estrogen and estrogen receptors in the modulation of gastrointestinal epithelial secretion
por: Yang, Xin, et al.
Publicado: (2017)

Estrogen, estrogen receptors, and hepatocellular carcinoma: Are we there yet?
por: Sukocheva, Olga A
Publicado: (2018)

Role of Estrogen and Estrogen Receptor in GH-Secreting Adenomas
por: Voltan, Giacomo, et al.
Publicado: (2023)

Estrogens, Estrogen Receptors and Tumor Microenvironment in Ovarian Cancer
por: Kozieł, Marta Justyna, et al.
Publicado: (2023)

Estrogens and Estrogen Receptor Modulators in Cancer Research and Therapy
por: Treeck, Oliver
Publicado: (2023)

Estrogen Receptors and Endometriosis
por: Chantalat, Elodie, et al.
Publicado: (2020)

Estrogen affects cell growth and IGF-1 receptor expression in renal cell carcinoma
por: Sun, Lijiang, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_4mvdo7a11mvmst4uslt6oduuun