Cargando…

Functional constraints on HIV-1 capsid: their impacts on the viral immune escape potency

In mature HIV-1 particles, viral capsid (CA) proteins form the conical core structure that encapsidates two copies of the viral RNA genome. After fusion of the viral envelope and cellular membranes, the CA core enters into the cytoplasm of the target cells. CA proteins then interact with a variety o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Takemura, Taichiro, Murakami, Tsutomu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2012
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474374/ https://www.ncbi.nlm.nih.gov/pubmed/23087682 http://dx.doi.org/10.3389/fmicb.2012.00369

Ejemplares similares

HIV Capsid Protein Genetic Diversity Across HIV-1 Variants and Impact on New Capsid-Inhibitor Lenacapavir
por: Troyano-Hernáez, Paloma, et al.
Publicado: (2022)

CTL Escape and Viral Fitness in HIV/SIV Infection
por: Seki, Sayuri, et al.
Publicado: (2012)

Acute Infection of Viral Pathogens and Their Innate Immune Escape
por: Rai, Kul Raj, et al.
Publicado: (2021)

Quantitative microscopy of functional HIV post-entry complexes reveals association of replication with the viral capsid
por: Peng, Ke, et al.
Publicado: (2014)

Mechanism of herpesvirus UL24 protein regulating viral immune escape and virulence
por: Ruan, Peilin, et al.
Publicado: (2023)

Comparison of Biochemical Properties of HIV-1 and HIV-2 Capsid Proteins
por: Miyazaki, Yasuyuki, et al.
Publicado: (2017)

Modulation of HIV-1 capsid multimerization by sennoside A and sennoside B via interaction with the NTD/CTD interface in capsid hexamer
por: Zhang, Da-Wei, et al.
Publicado: (2023)

DNA damage repair machinery and HIV escape from innate immune sensing
por: Brégnard, Christelle, et al.
Publicado: (2014)

The secrets of the stability of the HIV-1 capsid
por: Obr, Martin, et al.
Publicado: (2018)

HIV-1 capsid variability: viral exploitation and evasion of capsid-binding molecules
por: Saito, Akatsuki, et al.
Publicado: (2021)

HIV-1 Capsid Core: A Bullet to the Heart of the Target Cell
por: Toccafondi, Elenia, et al.
Publicado: (2021)

New Potent Membrane-Targeting Antibacterial Peptides from Viral Capsid Proteins
por: Dias, Susana A., et al.
Publicado: (2017)

Immune Escape Strategies of Malaria Parasites
por: Gomes, Pollyanna S., et al.
Publicado: (2016)

The Hepatitis E Virus Open Reading Frame 2 Protein: Beyond Viral Capsid
por: Zhou, Zhaobin, et al.
Publicado: (2021)

Leishmania Hijacks Myeloid Cells for Immune Escape
por: Martínez-López, María, et al.
Publicado: (2018)

Antibody escape by polyomavirus capsid mutation facilitates neurovirulence
por: Lauver, Matthew D, et al.
Publicado: (2020)

Gyrase B Inhibitor Impairs HIV-1 Replication by Targeting Hsp90 and the Capsid Protein
por: Vozzolo, Luciano, et al.
Publicado: (2010)

GS-CA Compounds: First-In-Class HIV-1 Capsid Inhibitors Covering Multiple Grounds
por: Singh, Kamal, et al.
Publicado: (2019)

HIV-1 capsid is the key orchestrator of early viral replication
por: Zila, Vojtech, et al.
Publicado: (2021)

Critical mechanistic features of HIV-1 viral capsid assembly
por: Gupta, Manish, et al.
Publicado: (2023)

Small-Molecule Anti-HIV-1 Agents Based on HIV-1 Capsid Proteins
por: Kobayakawa, Takuya, et al.
Publicado: (2021)

Development of potency, breadth and resilience to viral escape mutations in SARS-CoV-2 neutralizing antibodies
por: Muecksch, Frauke, et al.
Publicado: (2021)

Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways
por: Zhao, Fangzhu, et al.
Publicado: (2022)

Can the Bacterial Community of a High Arctic Glacier Surface Escape Viral Control?
por: Rassner, Sara M. E., et al.
Publicado: (2016)

Beclin-1 Targeting for Viral Immune Escape
por: Münz, Christian
Publicado: (2011)

Wastewater treatment plants, an “escape gate” for ESCAPE pathogens
por: Marutescu, Luminita Gabriela, et al.
Publicado: (2023)

Immune Escape by Non-coding RNAs of the Epstein Barr Virus
por: Münz, Christian
Publicado: (2021)

Enhancing the Clinical Potential of AAV Vectors by Capsid Engineering to Evade Pre-Existing Immunity
por: Bartel, Melissa, et al.
Publicado: (2011)

Viral escape in the CNS with multidrug-resistant HIV-1
por: Béguelin, Charles, et al.
Publicado: (2014)

Novel PF74-like small molecules targeting the HIV-1 capsid protein: Balance of potency and metabolic stability
por: Wang, Lei, et al.
Publicado: (2021)

Permeability of the HIV-1 capsid to metabolites modulates viral DNA synthesis
por: Xu, Chaoyi, et al.
Publicado: (2020)

Impacts of HIV Cure Interventions on Viral Reservoirs in Tissues
por: Denton, Paul W., et al.
Publicado: (2019)

The 4th and 112th Residues of Viral Capsid Cooperatively Modulate Capsid-CPSF6 Interactions of HIV-1
por: Saito, Akatsuki, et al.
Publicado: (2020)

Generation of a monoclonal antibody against duck circovirus capsid protein and its potential application for native viral antigen detection
por: Li, Jinxin, et al.
Publicado: (2023)

Co-expression of Ubiquitin gene and capsid protein gene enhances the potency of DNA immunization of PCV2 in mice
por: Fu, Fang, et al.
Publicado: (2011)

Low-molecular-weight anti-HIV-1 agents targeting HIV-1 capsid proteins
por: Kobayakawa, Takuya, et al.
Publicado: (2023)

Epitope length variants balance protective immune responses and viral escape in HIV-1 infection
por: Pymm, Phillip, et al.
Publicado: (2022)

Bo Zhong: Captive by the viral immune escape
por: Morgado-Palacin, Lucia
Publicado: (2022)

Enhancement of viral escape in HIV-1 Nef by STEP vaccination
por: Park, Sung Yong, et al.
Publicado: (2016)

Role of Trypanosoma cruzi Trans-sialidase on the Escape from Host Immune Surveillance
por: Nardy, Ana F. F. R., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_rd336rfrq5e20uusg8v0bv1n5f