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CD200R1 Supports HSV-1 Viral Replication and Licenses Pro-Inflammatory Signaling Functions of TLR2

The CD200R1:CD200 axis is traditionally considered to limit tissue inflammation by down-regulating pro-inflammatory signaling in myeloid cells bearing the receptor. We generated CD200R1(−/−) mice and employed them to explore both the role of CD200R1 in regulating macrophage signaling via TLR2 as wel...

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Detalles Bibliográficos
Autores principales: Soberman, Roy J., MacKay, Christopher R., Vaine, Christine A., Ryan, Glennice Bowen, Cerny, Anna M., Thompson, Mikayla R., Nikolic, Boris, Primo, Valeria, Christmas, Peter, Sheiffele, Paul, Aronov, Lisa, Knipe, David M., Kurt-Jones, Evelyn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474780/
https://www.ncbi.nlm.nih.gov/pubmed/23082204
http://dx.doi.org/10.1371/journal.pone.0047740

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