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Depletion of Regulatory T Lymphocytes Reverses the Imbalance between Pro- and Anti-Tumor Immunities via Enhancing Antigen-Specific T Cell Immune Responses
BACKGROUND: The regulatory T cells (Tregs) can actively suppress the immune responses. However, literature about detailed changes of host effective and suppressive immunities before and after depletion of Tregs in ovarian carcinomas, is rare. MATERIALS AND METHODS: Ovarian cancer patients and the as...
Autores principales: | Chen, Yu-Li, Chang, Ming-Cheng, Chen, Chi-An, Lin, Han-Wei, Cheng, Wen-Fang, Chien, Chung-Liang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474819/ https://www.ncbi.nlm.nih.gov/pubmed/23082146 http://dx.doi.org/10.1371/journal.pone.0047190 |
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