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Involvement of CXCR4 Chemokine Receptor in Metastastic HER2-Positive Esophageal Cancer
A functional linkage of the structurally unrelated receptors HER2 and CXCR4 has been suggested for breast cancer but has not been evaluated for esophageal carcinoma. The inhibition of HER2 leads to a reduction of primary tumor growth and metastases in an orthotopic model of esophageal carcinoma. The...
Autores principales: | Gros, Stephanie J., Kurschat, Nina, Drenckhan, Astrid, Dohrmann, Thorsten, Forberich, Evelyn, Effenberger, Katharina, Reichelt, Uta, Hoffman, Robert M., Pantel, Klaus, Kaifi, Jussuf T., Izbicki, Jakob R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474831/ https://www.ncbi.nlm.nih.gov/pubmed/23082154 http://dx.doi.org/10.1371/journal.pone.0047287 |
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