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Establishment of Inducible Wild Type and Mutant Myocilin-GFP-Expressing RGC5 Cell Lines
BACKGROUND: Myocilin is a gene linked directly to juvenile- and adult-onset open angle glaucoma. Mutations including Gln368stop (Q368X) and Pro370Leu (P370L) have been identified in patients. The exact role of myocilin and its functional association with glaucoma are still unclear. In the present st...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474840/ https://www.ncbi.nlm.nih.gov/pubmed/23082156 http://dx.doi.org/10.1371/journal.pone.0047307 |