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Natural history of gastric cancer—a case followed up for eight years: early to advanced gastric cancer
We experienced a case of gastric cancer that was prospectively followed up for 8 years. With severe heart disease, the patient did not wish surgery or anticancer drug treatment. After informed consent was obtained, he was followed up for 8 years. He received upper gastrointestinal endoscopy every ye...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Japan
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474902/ https://www.ncbi.nlm.nih.gov/pubmed/23087768 http://dx.doi.org/10.1007/s12328-012-0325-2 |
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author | Fujisaki, Junko Nakajima, Toshifusa Hirasawa, Toshiaki Yamamoto, Yorimasa Ishiyama, Akiyoshi Tsuchida, Tomohiro Hoshino, Etsuo Igarashi, Masahiro Yamaguchi, Toshiharu |
author_facet | Fujisaki, Junko Nakajima, Toshifusa Hirasawa, Toshiaki Yamamoto, Yorimasa Ishiyama, Akiyoshi Tsuchida, Tomohiro Hoshino, Etsuo Igarashi, Masahiro Yamaguchi, Toshiharu |
author_sort | Fujisaki, Junko |
collection | PubMed |
description | We experienced a case of gastric cancer that was prospectively followed up for 8 years. With severe heart disease, the patient did not wish surgery or anticancer drug treatment. After informed consent was obtained, he was followed up for 8 years. He received upper gastrointestinal endoscopy every year, which revealed IIc early gastric cancer, and biopsy showed well differentiated adenocarcinoma. A flat and mildly depressed lesion with redness was observed on endoscopy, exhibiting typical morphology of IIc-type early gastric cancer. The appearance of IIc M cancer was observed macroscopically from 2000 to 2003. Four years later, surface irregularity with ulceration appeared. Then, the whole lesion was elevated, which suggested submucosal invasion, and the tumor exhibited the morphology of IIa + IIc or type 3. The ulcer became deeper and elevated boundaries were formed. Horizontal expansion of the flat lesion was mild, while invasion to deeper layers was predominant. Eventually, he died of heart failure. Estimated M cancer was observed for about 3 years, followed by invasion to deeper layers. Taken together, this is a valuable case that followed up the manner of invasion to deeper layers over time from early to advanced gastric cancer. |
format | Online Article Text |
id | pubmed-3474902 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Springer Japan |
record_format | MEDLINE/PubMed |
spelling | pubmed-34749022012-10-18 Natural history of gastric cancer—a case followed up for eight years: early to advanced gastric cancer Fujisaki, Junko Nakajima, Toshifusa Hirasawa, Toshiaki Yamamoto, Yorimasa Ishiyama, Akiyoshi Tsuchida, Tomohiro Hoshino, Etsuo Igarashi, Masahiro Yamaguchi, Toshiharu Clin J Gastroenterol Case Report We experienced a case of gastric cancer that was prospectively followed up for 8 years. With severe heart disease, the patient did not wish surgery or anticancer drug treatment. After informed consent was obtained, he was followed up for 8 years. He received upper gastrointestinal endoscopy every year, which revealed IIc early gastric cancer, and biopsy showed well differentiated adenocarcinoma. A flat and mildly depressed lesion with redness was observed on endoscopy, exhibiting typical morphology of IIc-type early gastric cancer. The appearance of IIc M cancer was observed macroscopically from 2000 to 2003. Four years later, surface irregularity with ulceration appeared. Then, the whole lesion was elevated, which suggested submucosal invasion, and the tumor exhibited the morphology of IIa + IIc or type 3. The ulcer became deeper and elevated boundaries were formed. Horizontal expansion of the flat lesion was mild, while invasion to deeper layers was predominant. Eventually, he died of heart failure. Estimated M cancer was observed for about 3 years, followed by invasion to deeper layers. Taken together, this is a valuable case that followed up the manner of invasion to deeper layers over time from early to advanced gastric cancer. Springer Japan 2012-07-29 2012 /pmc/articles/PMC3474902/ /pubmed/23087768 http://dx.doi.org/10.1007/s12328-012-0325-2 Text en © The Author(s) 2012 https://creativecommons.org/licenses/by/4.0/ This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. |
spellingShingle | Case Report Fujisaki, Junko Nakajima, Toshifusa Hirasawa, Toshiaki Yamamoto, Yorimasa Ishiyama, Akiyoshi Tsuchida, Tomohiro Hoshino, Etsuo Igarashi, Masahiro Yamaguchi, Toshiharu Natural history of gastric cancer—a case followed up for eight years: early to advanced gastric cancer |
title | Natural history of gastric cancer—a case followed up for eight years: early to advanced gastric cancer |
title_full | Natural history of gastric cancer—a case followed up for eight years: early to advanced gastric cancer |
title_fullStr | Natural history of gastric cancer—a case followed up for eight years: early to advanced gastric cancer |
title_full_unstemmed | Natural history of gastric cancer—a case followed up for eight years: early to advanced gastric cancer |
title_short | Natural history of gastric cancer—a case followed up for eight years: early to advanced gastric cancer |
title_sort | natural history of gastric cancer—a case followed up for eight years: early to advanced gastric cancer |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474902/ https://www.ncbi.nlm.nih.gov/pubmed/23087768 http://dx.doi.org/10.1007/s12328-012-0325-2 |
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