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Structural and mechanistic investigations on Salmonella typhimurium acetate kinase (AckA): identification of a putative ligand binding pocket at the dimeric interface

BACKGROUND: Bacteria such as Escherichia coli and Salmonella typhimurium can utilize acetate as the sole source of carbon and energy. Acetate kinase (AckA) and phosphotransacetylase (Pta), key enzymes of acetate utilization pathway, regulate flux of metabolites in glycolysis, gluconeogenesis, TCA cy...

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Detalles Bibliográficos
Autores principales:	Chittori, Sagar, Savithri, Handanahal S, Murthy, Mathur RN
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475010/ https://www.ncbi.nlm.nih.gov/pubmed/23031654 http://dx.doi.org/10.1186/1472-6807-12-24

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