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Identification Of Small Molecule TRABID Deubiquitinase Inhibitors By Computation-Based Virtual Screen

BACKGROUND: Wnt/β-catenin-mediated gene transcription plays important roles in a wide range of biological and pathophysiological processes including tumorigenesis where β-catenin-mediated transcription activity frequently elevates. TRABID, a deubiquitinase, was shown to have a positive Wnt/β-catenin...

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Detalles Bibliográficos
Autores principales:	Shi, Tong, Bao, Ju, Wang, Nick X, Zheng, Jie, Wu, Dianqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475094/ https://www.ncbi.nlm.nih.gov/pubmed/22584113 http://dx.doi.org/10.1186/1472-6769-12-4

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