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A Chinese herbal formula "Gan-Lu-Yin" suppresses vascular smooth muscle cell migration by inhibiting matrix metalloproteinase-2/9 through the PI3K/AKT and ERK signaling pathways

BACKGROUND: This study was to explore the effects of Gan-Lu-Yin (GLY) on the migration of vascular smooth muscle cells (VSMCs) induced by fetal bovine serum and on neointima formation in a rat model of carotid artery balloon injury. METHODS: VSMCs were treated with different concentrations of GLY, a...

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Detalles Bibliográficos
Autores principales: Chien, Yi-Chung, Sheu, Ming-Jyh, Wu, Chieh-Hsi, Lin, Wen-Hsin, Chen, Ying-Yi, Cheng, Po-Liang, Cheng, Hsu-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475136/
https://www.ncbi.nlm.nih.gov/pubmed/22920190
http://dx.doi.org/10.1186/1472-6882-12-137