A comparison of different linkage statistics in small to moderate sized pedigrees with complex diseases

BACKGROUND: In the last years GWA studies have successfully identified common SNPs associated with complex diseases. However, most of the variants found this way account for only a small portion of the trait variance. This fact leads researchers to focus on rare-variant mapping with large scale sequ...

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Detalles Bibliográficos
Autores principales: Flaquer, Antònia, Strauch, Konstantin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475142/
https://www.ncbi.nlm.nih.gov/pubmed/22862841
http://dx.doi.org/10.1186/1756-0500-5-411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475142/
https://www.ncbi.nlm.nih.gov/pubmed/22862841
http://dx.doi.org/10.1186/1756-0500-5-411

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