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A comparison of different linkage statistics in small to moderate sized pedigrees with complex diseases
BACKGROUND: In the last years GWA studies have successfully identified common SNPs associated with complex diseases. However, most of the variants found this way account for only a small portion of the trait variance. This fact leads researchers to focus on rare-variant mapping with large scale sequ...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475142/ https://www.ncbi.nlm.nih.gov/pubmed/22862841 http://dx.doi.org/10.1186/1756-0500-5-411 |