Meroterpenes from Endophytic Fungus A1 of Mangrove Plant Scyphiphora hydrophyllacea

Four new meroterpenes, guignardones F–I (1–4), together with two known compounds guignardones A (5) and B (6) were isolated from the endophytic fungus A1 of the mangrove plant Scyphiphora hydrophyllacea. Their structures and relative configurations were elucidated by spectroscopic data and single-cr...

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Autores principales: Mei, Wen-Li, Zheng, Bo, Zhao, You-Xing, Zhong, Hui-Ming, Chen, Xun-Li Wu, Zeng, Yan-Bo, Dong, Wen-Hua, Huang, Jiu-Li, Proksch, Peter, Dai, Hao-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475268/
https://www.ncbi.nlm.nih.gov/pubmed/23118716
http://dx.doi.org/10.3390/md10091993
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author Mei, Wen-Li
Zheng, Bo
Zhao, You-Xing
Zhong, Hui-Ming
Chen, Xun-Li Wu
Zeng, Yan-Bo
Dong, Wen-Hua
Huang, Jiu-Li
Proksch, Peter
Dai, Hao-Fu
author_facet Mei, Wen-Li
Zheng, Bo
Zhao, You-Xing
Zhong, Hui-Ming
Chen, Xun-Li Wu
Zeng, Yan-Bo
Dong, Wen-Hua
Huang, Jiu-Li
Proksch, Peter
Dai, Hao-Fu
author_sort Mei, Wen-Li
collection PubMed
description Four new meroterpenes, guignardones F–I (1–4), together with two known compounds guignardones A (5) and B (6) were isolated from the endophytic fungus A1 of the mangrove plant Scyphiphora hydrophyllacea. Their structures and relative configurations were elucidated by spectroscopic data and single-crystal X-ray crystallography. A possible biogenetic pathway of compounds 1–6 was also proposed. All compounds were evaluated for inhibitory activity against methicillin-resistant Staphylococcus aureus (MRSA) and Staphylococcus aureus.
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spelling pubmed-34752682012-11-01 Meroterpenes from Endophytic Fungus A1 of Mangrove Plant Scyphiphora hydrophyllacea Mei, Wen-Li Zheng, Bo Zhao, You-Xing Zhong, Hui-Ming Chen, Xun-Li Wu Zeng, Yan-Bo Dong, Wen-Hua Huang, Jiu-Li Proksch, Peter Dai, Hao-Fu Mar Drugs Article Four new meroterpenes, guignardones F–I (1–4), together with two known compounds guignardones A (5) and B (6) were isolated from the endophytic fungus A1 of the mangrove plant Scyphiphora hydrophyllacea. Their structures and relative configurations were elucidated by spectroscopic data and single-crystal X-ray crystallography. A possible biogenetic pathway of compounds 1–6 was also proposed. All compounds were evaluated for inhibitory activity against methicillin-resistant Staphylococcus aureus (MRSA) and Staphylococcus aureus. MDPI 2012-09-17 /pmc/articles/PMC3475268/ /pubmed/23118716 http://dx.doi.org/10.3390/md10091993 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Mei, Wen-Li
Zheng, Bo
Zhao, You-Xing
Zhong, Hui-Ming
Chen, Xun-Li Wu
Zeng, Yan-Bo
Dong, Wen-Hua
Huang, Jiu-Li
Proksch, Peter
Dai, Hao-Fu
Meroterpenes from Endophytic Fungus A1 of Mangrove Plant Scyphiphora hydrophyllacea
title Meroterpenes from Endophytic Fungus A1 of Mangrove Plant Scyphiphora hydrophyllacea
title_full Meroterpenes from Endophytic Fungus A1 of Mangrove Plant Scyphiphora hydrophyllacea
title_fullStr Meroterpenes from Endophytic Fungus A1 of Mangrove Plant Scyphiphora hydrophyllacea
title_full_unstemmed Meroterpenes from Endophytic Fungus A1 of Mangrove Plant Scyphiphora hydrophyllacea
title_short Meroterpenes from Endophytic Fungus A1 of Mangrove Plant Scyphiphora hydrophyllacea
title_sort meroterpenes from endophytic fungus a1 of mangrove plant scyphiphora hydrophyllacea
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475268/
https://www.ncbi.nlm.nih.gov/pubmed/23118716
http://dx.doi.org/10.3390/md10091993
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