Briacavatolides D–F, New Briaranes from the Taiwanese Octocoral Briareum excavatum

In the continued search for novel bioactive substances from the Taiwanese octocoral Briareum excavatum collected at Orchid Island, three new briarane-type diterpenoids, briacavatolides D–F (1–3) were isolated from the acetone extract. The structures of these compounds were elucidated by extensive NM...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Shang-Kwei, Yeh, Tsun-Tai, Duh, Chang-Yih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475276/
https://www.ncbi.nlm.nih.gov/pubmed/23118724
http://dx.doi.org/10.3390/md10092103
Descripción
Sumario:In the continued search for novel bioactive substances from the Taiwanese octocoral Briareum excavatum collected at Orchid Island, three new briarane-type diterpenoids, briacavatolides D–F (1–3) were isolated from the acetone extract. The structures of these compounds were elucidated by extensive NMR spectroscopic analysis and physical data. The anti-HCMV (human cytomegalovirus) activity of 1–3 and their cytotoxicity against selected cancer cell lines were evaluated.

Ejemplares similares